• Recherche translationnelle en santé,


    technologie pour la santé et recherche clinique

    https://tonic.inserm.fr/wp-content/uploads/2019/09/MelaPlanton-150x150.jpeg
       

    Mélanie PLANTON

    Psychologue, PhD

    Psychologue spécialisée en neuropsychologie, Département de neurologie, Hôpital Pierre Paul Riquet, CHU Purpan, Toulouse

     

    Coordonnées

    Laboratoire ToNIC, UMR 1214, CHU PURPAN – Pavillon BAUDOT, Place du Dr Joseph Baylac, 31024 TOULOUSE CEDEX 3

    Département de Neurologie, Unité de neuropsychologie, Hôpital Pierre Paul Riquet, Place du Dr Joseph Baylac, 31059 TOULOUSE CEDEX 9

     

    Disciplines

    Psychologie, Neurosciences

     

    Thèmes de recherche

    Mes axes de recherche suivent une logique en trois temps, à savoir observer, comprendre et agir.

    Axe 1 : Caractérisation neuropsychologique et physiopathologique des troubles cognitifs après une lésion cérébrale acquise (AVC, TCC) et dans les troubles du neurodéveloppement de l’adolescent et de l’adulte

    Axe 2 : Organisation et réorganisation neuronale après une lésion cérébrale acquise

    Axe 3 : Modulation des mécanismes de plasticité cérébrale (approches en remédiation cognitive et neurostimulation) après une lésion cérébrale acquise

     

    Curriculum Vitae

    Parcours académique

    2024 : HDR ‘Troubles cognitifs d’origine vasculaire et traumatique : des mécanismes physiopathologiques à la remédiation cognitive’. (Université Toulouse 3)

    2013 : Doctorat en neurosciences (Université Toulouse 3)

    2009 : Master 2 Neuropsychologie et Neurosciences Cliniques (Université Toulouse 3)

    2008 : Master 2 Psychologie mention neuropsychologie (Université d’Angers)

     

    Responsabilités pédagogiques

    Depuis 2020 : Co-responsable du master 2 Neuropsychologie et Neurosciences Cliniques, Toulouse 3.

     

    Financements 

    2023      Investigateur principal (14k) Influence du polymorphisme des gènes codant pour le BDNF et l’apolipoprotéine E sur la récupération cognitive et fonctionnelle des patients après un traumatisme crânien modéré à sévère.

    2023      Investigateur principal (30k) Sommeil et consolidation mnésique chez l’adulte avec un trouble du déficit de l’attention avec hyperactivité.

    2017      Responsable scientifique (49k) Effet de la remédiation cognitive combinée à la stimulation tDCS après un traumatisme crânien modéré à sévère.

     

    Publications (articles scientifiques publiés dans des revues à comité de lecture)

    29. Siguier P, Planton M, Baudou E, Chaix Y, Rafiq M, Wolfrum M, Jucla m ? Pariente J. Ageing Resaerch Reviews (in press).
    28. Giroud M*, Planton M*, Herve D, Bonneville F, Mirabel H, Pariente J, Péran P, Calviere L. MRI hypoperfusion as cognitive impairment in adults with MoyaMoya angiopathy. European Journal of Neurology. 2024, 23969873241240829
    27. Raposo N, Periole C, Planton M. In vivo diagnosis of cerebral angiopathy amyloid. Current Opinion in Neurology. 2023.
    26. Laguitton V, Boutin M, Brissart H, et al. Neuropsychological assessment in pediatric epilepsy surgery: A French procedure consensus. Revue Neurologique. 2023.
    25. Julien A, Tessier S, Tisserand C, Péran P, Planton M, Pariente J, & Brauge D. Effects of sociodemographic and player characteristics on baseline cognitive performance in 1000 rugby players: A retrospective 8-year follow-up study. Journal of science and medicine in sport. 2023; S1440-2440 (1423) 00414-00410.
    24. Gouilly D, Salabert AS, Bertrand E, Goubeaud M, Catala H, Germain J, Carlier J, Nogueira L, Planton M, Hitzel A, Méligne D, Sarton B, Silva S, Lemesle B, Payoux P, Thalamas C, Péran P, Pariente J. Clinical heterogeneity of neuro-inflammatory PET profiles in early Alzheimer’s disease. Frontiers in Neurology. 2023, 14.
    23. Julien A, Danet L, Loisel M, Brauge D, Pariente J, Péran P, & Planton M. Update on the efficacy of cognitive rehabilitation following moderate to severe traumatic brain injury: a scoping review. Archives of physical medicine and rehabilitation 2022.
    22. Planton M, Lemesle B, Cousineau M, et al. The role of neuropsychological assessment in adults with attention deficit/hyperactivity disorders. Revue Neurologique 2021.
    21. Planton M, Pariente J, Nemmi F, et al. Interhemispheric distribution of amyloid and small vessel disease burden in cerebral amyloid angiopathy‐related intracerebral hemorrhage. European journal of neurology. 2020;27:1664-1671.
    20. Calviere L, Loubiere P, Planton M, Cazzola V, Catalaa I, Mirabel H et al. Decreased frontal white-matter diffusion and improved cognitive flexibility after burr-hole surgery in moyamoya angiopathy. BMC neurology. 2020;20(1):1-9.
    19. Raposo N, Planton M, Siegfried A, et al. Amyloid-β transmission through cardiac surgery using cadaveric dura mater patch. Journal of Neurology, Neurosurgery & Psychiatry. 2020;91:440-441.
    18. Planton M, Saint-Aubert L, Raposo N, et al. Florbetapir Regional Distribution in Cerebral Amyloid Angiopathy and Alzheimer’s Disease: A PET Study. Journal of Alzheimer’s Disease: JAD. 2020;73:1607-1614.
    17. Brissart H, Planton M, Bilger M, Bulteau C, Forthoffer N, Guinet V, Hennion S, Kleitz C, Laguitton V, Mirabel H et al. French neuropsychological procedure consensus in epilepsy surgery. Epilepsy & Behavior. 2019;100, 106522.
    16. Raposo N, Planton M, Payoux P, Péran P, Albucher J, Calviere L, Viguier A, Rousseau V, Hitzel A, Chollet F. Enlarged perivascular spaces and florbetapir uptake in patients with intracerebral hemorrhage. European journal of nuclear medicine and molecular imaging. 2019; 46, 2339.
    15. Calviere L, Viguier A, Patsoura S, Rousseau V, Albucher J, Planton M, Pariente J, Cognard C, Olivot J, Bonneville F. Risk of Intracerebral Hemorrhage and Mortality After Convexity Subarachnoid Hemorrhage in Cerebral Amyloid Angiopathy. Stroke. 2019; STROKEAHA119026244.
    14. Blanc C, Viguier A, Calviere L, Planton M, Albucher J-F, Rousseau V et al. Underlying Small Vessel Disease Associated With Mixed Cerebral Microbleeds. Frontiers in neurology. 2019;10:1126.
    13. Raposo N, Calviere L, Cazzola V, Planton M, Patsoura S, Wargny M, et al. Cortical superficial siderosis and acute convexity subarachnoid hemorrhage in cerebral amyloid angiopathy. European journal of neurology. 2018;25(2):253-9.
    12. Guerrier L, Men JL, Gane A, Planton M, Salabert A-S, Payoux P, et al. Involvement of the Cingulate Cortex in Anosognosia: A Multimodal Neuroimaging Study in Alzheimer’s Disease Patients. Journal of Alzheimer’s Disease. 2018:1-11.
    11. Raposo N*, Planton M*, Péran P, Payoux P, Bonneville F, Lyoubi A, Albucher JF, Acket B, Salabert AS, Olivot JM. Florbetapir imaging in cerebral amyloid angiopathy-related hemorrhages. Neurology. 2017:10.1212/WNL. 0000000000004228.
    10. Planton M, Saint-Aubert L, Raposo N, Branchu L, Lyoubi A, Bonneville F, Albucher J-F, Olivot J-M, Péran P, Pariente J. High prevalence of cognitive impairment after intracerebral hemorrhage. PloS one. 2017;12:e0178886.
    9. Planton M, Raposo N, Albucher J-F, Pariente J. Cerebral amyloid angiopathy-related cognitive impairment: The search for a specific neuropsychological pattern. Revue neurologique. 2017; 173:562-565.
    8. Lemesle B, Planton M, Pagès B, Pariente J. Accelerated long-term forgetting and autobiographical memory disorders in temporal lobe epilepsy: One entity or two? Revue neurologique. 2017;173(7-8):498-505.
    7. Planton M, Raposo N, Danet L, Albucher J-F, Péran P, Pariente J. Impact of spontaneous intracerebral hemorrhage on cognitive functioning: An update. Revue neurologique. 2017;173(7-8):481-9.
    6. Danet L, Barbeau EJ, Eustache P, Planton M, Raposo N, Sibon I, Albucher J-F, Bonneville F, Péran P, Pariente J. Thalamic amnesia after infarct the role of the mammillothalamic tract and mediodorsal nucleus. Neurology. 2015:10.1212/WNL. 0000000000002226.
    5. Pages B, Planton M, Buys S, Lemesle B, Birmes P, Barbeau EJ, Maziero S, Cordier L, Cabot C, Puel M. Neuropsychological outcome after carbon monoxide exposure following a storm: A case-control study. BMC neurology. 2014;14:153.
    4. Planton M, Pariente J. Neuropsychological outcome after a first symptomatic ischaemic stroke in patients with good recovery: Answer to re mark’s letter. European Journal of Neurology. 2012;19:e62-e62.
    3. Saint-Aubert L, Planton M, Hannequin D, Albucher JF, Delisle MB, Payoux P, Hitzel A, Viallard G, Péran P, Campion D. Amyloid imaging with av45 (18 f-florbetapir) in a cognitively normal AβPP duplication carrier. Journal of Alzheimer’s Disease. 2012;28:877-883.
    2. Godefroy O, Leclercq C, Roussel M, Moroni C, Quaglino V, Beaunieux H et al. French adaptation of the vascular cognitive impairment harmonization standards: the GRECOG-VASC study. International Journal of Stroke. 2012;7(4):362-3.
    1. Planton M, Peiffer S, Albucher J, Barbeau E, Tardy J, Pastor J, Januel A, Bezy C, Lemesle B, Puel M. Neuropsychological outcome after a first symptomatic ischaemic stroke with ‘good recovery’. European Journal of Neurology. 2011;19:212-219.

     

      Abstracts rédigés ou co-rédigés

    • > Characterization of the perceptual-motor procedural learning deficit in adults with probable Developmental Coordination Disorder and links with motor, executive, attentional functions and comorbidities

      S. Seiwert, E. Martin, M. Planton, D. Méligne, J. Pariente, J. Tisseyre, J. Tallet.

      FENS Regional Meeting FRM 2023

      Algarve Portugal

    • > Characterization of the perceptual-motor procedural learning deficit in adults with probable Developmental Coordination Disorder.

      S. Seiwert, E. Martin, M. Planton, D. Méligne, J. Pariente, J. Tisseyre, J. Tallet

      FENS Regional Meeting FRM 2023

      Algarve Portugal

    • > Amyloid imaging in cerebral amyloid angiopathy –related intracerebral haemorrhage and Alzheimer’s disease: a voxel-wise approach.

      Mélanie PLANTON, Laure Saint-Aubert, Nicolas Raposo, Pierre Payoux, Jean-Francois Albucher, Jean Marc Olivot, Patrice Péran, and Jérémie Pariente

      5th Congress of the European Academy of Neurology, EAN 2019, 29 juin- 2 Juillet 2019 à Oslo, Norvège.
    • > Cortex cingulaire et anosognosie dans la Maladie d’Alzheimer : étude en imagerie multimodale

      Laura Guerrier, Johanne Le Men, Anaïs Gane, Mélanie Planton, Anne-Sophie Salabert, Pierre Payoux, Hervé Dumas, Fabrice Bonneville, Patrice Péran, Jérémie Pariente

      41ièmes Journées de Printempsde SNLF - GRENOBLE Obtenu Prix de la meilleure communication orale
    • > Neuropsychological outcome after lobar and deep spontaneous intracerebral hemorrhage

      Mélanie Planton (PhD), Laure Saint-Aubert (PhD), Nicolas Raposo (MD), Laura Branchu (MsC), Aicha Lyoubi (MD), Jean-François Albucher (MD), Jérémie Pariente (MD, PhD)

      5th International Cerebral Amyloid Angiopathy - BOSTON

      Publications rédigées ou co-rédigées

    • > 73- Galantamine combined with cognitive rehabilitation on post-stroke cognitive impairment: a proof-of-concept study.

      Planton M, Nemmi F, Pages B, Albucher JF, Raposo N, Danet L, Péran P, Pariente J.

      Brain Inj. 2024 Oct 3:1-10. doi: 10.1080/02699052.2024.2409355.
    • > 67- Diffusion tensor imaging and gray matter volumetry to evaluate cerebral remodeling processes after a pure motor stroke: a longitudinal study.

      Loubinoux I, Lafuma M, Rigal J, Colitti N, Albucher JF, Raposo N, Planton M, Olivot JM, Chollet F.

      J Neurol. 2024 Sep 3. doi: 10.1007/s00415-024-12648-y.
    • > 58- Prevalence and characteristics of vascular cognitive impairment in a European cohort of adult patients with Moyamoya angiopathy.

      Giroud M, Calviere L, Machado C, Reyes S, Mirabel H, Raposo N, Brandicourt P, Viguier A, Albucher JF, Bonneville F, Olivot JM, Péran P, Pariente J, Hervé D, Planton M.

      J Neurol. 2024 Jul 17. doi: 10.1007/s00415-024-12555-2.
    • > 50- Can neurodevelopmental disorders influence the course of neurodegenerative diseases? A scoping review.

      Siguier PLM, Planton M, Baudou E, Chaix Y, Delage A, Rafiq M, Wolfrum M, Gérard F, Jucla M, Pariente J.

      Ageing Res Rev. 2024 Jun 8:102354. doi: 10.1016/j.arr.2024.102354.
    • > 49- Translocator protein (TSPO) genotype does not change cerebrospinal fluid levels of glial activation, axonal and synaptic damage markers in early Alzheimer’s disease.

      Gouilly D, Vrillon A, Bertrand E, Goubeaud M, Catala H, Germain J, Ainaoui N, Rafiq M, Nogueira L, Mouton-Liger F, Planton M, Salabert AS, Hitzel A, Méligne D, Jasse L, Sarton B, Silva S, Lemesle B, Péran P, Payoux P, Thalamas C, Paquet C, Pariente J.

      Neuroimage Clin. 2024 May 31;43:103626. doi: 10.1016/j.nicl.2024.103626.
    • > 24- MRI hypoperfusion as a determinant of cognitive impairment in adults with Moyamoya angiopathy.

      Giroud M, Planton M, Darcourt J, Raposo N, Brandicourt P, Mirabel H, Hervé D, Viguier A, Albucher JF, Pariente J, Olivot JM, Bonneville F, Péran P, Calviere L.

      Eur Stroke J. 2024 Mar 19:23969873241240829. doi: 10.1177/23969873241240829.
    • > 7- In-vivo diagnosis of cerebral amyloid angiopathy: an updated review.

      Raposo N, Périole C, Planton M.

      Curr Opin Neurol. 2024 Feb 1;37(1):19-25. doi: 10.1097/WCO.0000000000001236
    • > 69- Effects of sociodemographic and player characteristics on baseline cognitive performance in 1000 rugby players: A retrospective 8-year follow-up study.

      Julien A, Tessier S, Tisserand C, Péran P, Planton M, Pariente J, Brauge D.

      J Sci Med Sport. 2023 Sep 21:S1440-2440(23)00414-0. doi: 10.1016/j.jsams.2023.09.013.
    • > 59- Clinical heterogeneity of neuro-inflammatory PET profiles in early Alzheimer’s disease.

      Gouilly D, Salabert AS, Bertrand E, Goubeaud M, Catala H, Germain J, Ainaoui N, Rafiq M, Benaiteau M, Carlier J, Nogueira L, Planton M, Hitzel A, Méligne D, Sarton B, Silva S, Lemesle B, Payoux P, Thalamas C, Péran P, Pariente J.

      Front Neurol. 2023 Jul 31;14:1189278. doi: 10.3389/fneur.2023.1189278.
    • > 54- Update on the efficacy of cognitive rehabilitation following moderate to severe traumatic brain injury: a scoping review.

      Julien A, Danet L, Loisel M, Brauge D, Pariente J, Péran P, Planton M.

      Arch Phys Med Rehabil. 2022 Jul 31:S0003-9993(22)00533-0. doi: 10.1016/j.apmr.2022.07.007
    • > 15- The role of neuropsychological assessment in adults with attention deficit/hyperactivity disorders.

      Planton M, Lemesle B, Cousineau M, Carlier J, Milongo-Rigal E, Carle-Toulemonde G, Salles J, Pariente J.
      Voir la publication

      Rev Neurol (Paris). 2021 Feb 19:S0035-3787(21)00042-4. doi: 10.1016/j.neurol.2021.01.006.
    • > 26- Interhemispheric distribution of amyloid and small vessel disease burden in cerebral amyloid angiopathy-related intracerebral hemorrhage.

      Planton M, Pariente J, Nemmi F, Albucher JF, Calviere L, Viguier A, Olivot JM, Salabert AS, Payoux P, Peran P, Raposo N.
      Voir la publication

      Eur J Neurol. 2020 May 11. doi: 10.1111/ene.14301.
    • > 20- Decreased frontal white-matter diffusion and improved cognitive flexibility after burr-hole surgery in moyamoya angiopathy.

      Calviere L, Loubiere P, Planton M, Cazzola V, Catalaa I, Mirabel H, Sol JC, Bonneville F.
      Voir la publication

      BMC Neurol. 2020 Jan 20;20(1):30. doi: 10.1186/s12883-020-1614-x.
    • > 14- Risk of Intracerebral Hemorrhage and Mortality After Convexity Subarachnoid Hemorrhage in Cerebral Amyloid Angiopathy.

      Calviere L, Viguier A, Patsoura S, Rousseau V, Albucher JF, Planton M, Pariente J, Cognard C, Olivot JM, Bonneville F, Raposo N.
      Voir la publication

      Stroke. 2019 Sep;50(9):2562-2564. doi: 10.1161/STROKEAHA.119.026244.
    • > 2- Amyloid-β transmission through cardiac surgery using cadaveric dura mater patch.

      Raposo N, Planton M, Siegfried A, Calviere L, Payoux P, Albucher JF, Viguier A, Delisle MB, Uro-Coste E, Chollet F, Bonneville F, Olivot JM, Pariente J.
      Voir la publication

      J Neurol Neurosurg Psychiatry. 2020 Jan 20. pii: jnnp-2019-321927. doi: 10.1136/jnnp-2019-321927.
    • > 1- Florbetapir Regional Distribution in Cerebral Amyloid Angiopathy and Alzheimer’s Disease: A PET Study.

      Planton M, Saint-Aubert L, Raposo N, Payoux P, Salabert AS, Albucher JF, Olivot JM, Péran P, Pariente J.
      Voir la publication

      J Alzheimers Dis. 2020 Jan 13. doi: 10.3233/JAD-190625.
    • > 54- Underlying Small Vessel Disease Associated With Mixed Cerebral Microbleeds.

      Blanc C, Viguier A, Calviere L, Planton M, Albucher JF, Rousseau V, Sommet A, Bonneville F, Pariente J, Olivot JM, Raposo N.
      Voir la publication

      Front Neurol. 2019 Oct 23;10:1126. doi: 10.3389/fneur.2019.01126.
    • > 68- French neuropsychological procedure consensus in epilepsy surgery.

      Brissart H, Planton M, Bilger M, Bulteau C, Forthoffer N, Guinet V, Hennion S, Kleitz C, Laguitton V, Mirabel H, Mosca C, Pécheux N, Pradier S, Samson S, Tramoni E, Voltzenlogel V, Denos M, Boutin M.
      <a
      Voir la publication

      Epilepsy Behav. 2019 Nov;100(Pt A):106522. doi: 10.1016/j.yebeh.2019.106522. Epub 2019 Oct 15.
    • > 42- Enlarged perivascular spaces and florbetapir uptake in patients with intracerebral hemorrhage.

      Raposo N, Planton M, Payoux P, Péran P, Albucher JF, Calviere L, Viguier A, Rousseau V, Hitzel A, Chollet F, Olivot JM, Bonneville F, Pariente J.
      Voir la publication

      Eur J Nucl Med Mol Imaging. 2019 Jul 29. doi: 10.1007/s00259-019-04441-1.
    • > 24- Impact of spontaneous intracerebral hemorrhage on cognitive functioning: An update.

      Planton M, Raposo N, Danet L, Albucher JF, Péran P, Pariente J.

      Rev Neurol (Paris). 2017 Jul - Aug;173(7-8):481-489. doi: 10.1016/j.neurol.2017.06.010. Epub 2017 Aug 31. Review.
    • > 37- Involvement of the Cingulate Cortex in Anosognosia: A Multimodal Neuroimaging Study in Alzheimer’s Disease Patients.

      Guerrier L, Men JL, Gane A, Planton M, Salabert AS, Payoux P, Dumas H, Bonneville F, Péran P, Pariente J.

      J Alzheimers Dis. 2018 Jul 20. doi: 10.3233/JAD-180324.
    • > 9- Cortical superficial siderosis and acute convexity subarachnoid hemorrhage in cerebral amyloid angiopathy.

      Raposo N, Calviere L, Cazzola V, Planton M, Patsoura S, Wargny M, Albucher JF, Sommet A, Olivot JM, Chollet F, Pariente J, Bonneville F, Viguier A.

      Eur J Neurol. 2018 Feb;25(2):253-259. doi: 10.1111/ene.13484. Epub 2017 Nov 23.
    • > 54- Cortical superficial siderosis and acute convexity subarachnoid hemorrhage in cerebral amyloid angiopathy.

      Raposo N, Calviere L, Cazzola V, Planton M, Patsoura S, Wargny M, Albucher JF, Sommet A, Olivot JM, Chollet F, Pariente J, Bonneville F, Viguier A.

      Eur J Neurol. 2017 Oct 20. doi: 10.1111/ene.13484.
    • > 51- Cerebral amyloid angiopathy-related cognitive impairment: The search for a specific neuropsychological pattern.

      Planton M, Raposo N, Albucher JF, Pariente J.

      Rev Neurol (Paris). 2017 Oct 6. pii: S0035-3787(17)30733-6. doi: 10.1016/j.neurol.2017.09.006.
    • > 43- Impact of spontaneous intracerebral hemorrhage on cognitive functioning: An update.

      Planton M, Raposo N, Danet L, Albucher JF, Péran P, Pariente J. Rev Neurol (Paris).

      2017 Aug 21. pii: S0035-3787(17)30543-X. doi: 10.1016/j.neurol.2017.06.010.
    • > 38- Florbetapir imaging in cerebral amyloid angiopathy-related hemorrhages.

      Raposo N, Planton M, Péran P, Payoux P, Bonneville F, Lyoubi A, Albucher JF, Acket B, Salabert AS, Olivot JM, Hitzel A, Chollet F, Pariente J.

      Neurology. 2017 Jul 19. pii: 10.1212/WNL.0000000000004228. doi: 10.1212/WNL.0000000000004228.
    • > 27- High prevalence of cognitive impairment after intracerebral hemorrhage.

      Planton M, Saint-Aubert L, Raposo N, Branchu L, Lyoubi A, Bonneville F, Albucher JF, Olivot JM, Péran P, Pariente J.

      PLoS One. 2017 Jun 1;12(6):e0178886. doi: 10.1371/journal.pone.0178886. eCollection 2017.
    • > Thalamic amnesia after infarct: The role of the mammillothalamic tract and mediodorsal nucleus.

      Danet L, Barbeau EJ, Eustache P, Planton M, Raposo N, Sibon I, Albucher JF, Bonneville F, Peran P, Pariente J.

      Neurology. 2015 Dec 15;85(24):2107-15. doi: 10.1212/WNL.0000000000002226.