Recherche translationnelle en santé,
technologie pour la santé et recherche clinique
Patrice PÉRAN
Follow @PatricePeran
- > Nos équipes de recherche / Equipe DEVIN
- > Equipe DEVIN / Axe 1 : Développement de biomarqueurs en IRM
- > Equipe DEVIN / Axe 3 : Diagnostic et progression des syndromes parkinsoniens
- > Equipe DEVIN / Axe 4 : Physiopathologie de la dépression
- > Equipe DEVIN / Axe 5 : Mécanismes et substrats des déficits de mémoire
- > Equipe DEVIN / Axe 6 : Substrats neuronaux et pronostiques des patients comateux
- > Equipe DEVIN / Axe 7 : Physiopathologie des troubles neuro-développementaux
- > Equipe DEVIN / Titulaires & Contractuels
Travaille sur
- > Effect of Neflamapimod on neuroinflammation using DPA-714 in PET scan in selected Alzheimer disease patients.
Dominique Gouilly, Béatrice Lemesle, Pomies Elsa, Johanne Germain, Pierre Payoux, Mathieu Tafani, Anne-Sophie Brun-Salabert, Claire Thalamas, Marie Benaiteau, Jasmine Carlier, Fabienne Calvas, Patrice Péran, Jérémie Pariente
4th Nuclear Technologies for Health Symposium, 13-14 février 2020, Nantes
- > Multimodal MRI-PET data-driven pipeline for the discrimination of prodromal Alzheimer’s Disease
Federico Nemmi, Pierre Payoux, Jérémie Pariente, Patrice Péran
9th ECCN, 2-3 mars 2020, Parisff
- > Preliminary results : effect of p38α MAPK inhibitor on neuroinflammation assessed by DPA-714 in early Alzheimer disease
Dominique Gouilly , Béatrice Lemesle, Elsa Pomies , Johanne Germain, Pierre Payoux , Mathieu Tafani, Anne-Sophie Brun-Salabert , Claire Thalamas, Marie Benaiteau , Jasmine Carlier, Fabienne Calvas , Patrice Péran , Jérémie Pariente.
8èmes Rencontres de la Fondation Alzheimer, 19-20 novembre 2019, Paris
- > A bi-compartmental model to resolve R2* relaxometry
Michaud M., Arribarat G., Boucher S., Péran P.
– 36th Congress of the European Society for Magnetic Resonance in Medicine and Biology, ESMRMB 2019, 3 octobre – 5 octobre 2019 à Rotterdam, Pays-Bas.– Journées du GdR Mi2B/SFPM 2019 novembre 2019 à Nantes, France
- > Amyloid imaging in cerebral amyloid angiopathy –related intracerebral haemorrhage and Alzheimer’s disease: a voxel-wise approach.5th Congress of the European Academy of Neurology, EAN 2019, 29 juin- 2 Juillet 2019 à Oslo, Norvège.
Mélanie PLANTON, Laure Saint-Aubert, Nicolas Raposo, Pierre Payoux, Jean-Francois Albucher, Jean Marc Olivot, Patrice Péran, and Jérémie Pariente
- > Absence of correlation between complaint and visual alterations in PCA patients: A FGD-PET controlled study.5th Congress of the European Academy of Neurology, EAN 2019, 29 juin- 2 Juillet 2019 à Oslo, Norvège.
Guerrier L., Cransac C., Pagès B., Saint-Aubert L., Payoux P.,Péran P., Pariente J.
- > A whole-brain multimodal discrimination of Parkinsons dDiseas, Multiple System Atrophy and Controls.Organization for Human Brain Mapping,OHBM 2019, 9-13 juin 2019 à Rome, Italie.
F Nemmi, A Pavy-Le Traon, O Phillips, M Galitzky, W Meissner, O Rascol, P Péran
- > Discriminating neurofibromatosis and healthy children with multimodal MRI and machine learning.Organization for Human Brain Mapping,OHBM 2019, 9-13 juin 2019 à Rome, Italie.
F Nemmi, F Cignetti, C Assaiante, S Maziero, F Audic, P Péran, Y Chaix.
- > Learning and retention of a temporal sequence in children with Developmental Coordination Disorder depend on the modality (auditory vs visual) of stimulations.13th World Congress on Developmental Coordination Disorder DCD13. 5-8th June, University of Jyväskylä, Finland.
Lê M, Blais M, Maziero, S, Jucla M, Biotteau M, Albaret J-M, Péran P, Chauveau N, Chaix Y, Tallet J
- > Amélioration de la relaxométrie R2* avec la prise en compte d’une composante bi-compartimentale.4ème Congrès de la Société Française de Résonance Magnétique en Biologie & Médecine - SFRMBM 2019 - 19-21 Mars 2019 à Strasbourg.
Michaud M., Arribarat G., Boucher S., Péran P.
- > Optimisation de l’acquisition IRM multiparamétrique dédiée au Tronc Cérébral.4ème Congrès de la Société Française de Résonance Magnétique en Biologie & Médecine - SFRMBM 2019 - 19-21 Mars 2019 à Strasbourg.
Arribarat, G., De Barros, A., Michaud, M., Favé, Y., Gros-Dagnac, H,. Lotterie, J-A., Péran, P.
- > Correlation between glucose metabolism and visual complaint in posterior cortical atrophy. A FGD-PET study.Réunion Francophone sur la Maladie d’Alzheimer & les Syndrome Apparentés (RFMASA). 11-14 Juin 2018, Lille, France.
Guerrier L., Cransac C., Pagès B., Saint-Aubert L., Péran P., Pariente J.
- > Longitudinal changes of R2 star and diffusion parameters in substantia nigra of Parkinson’s disease patients.8th European Conference onClinical Neuroimaging, 20-21 Mai 2018, Bruxelles, Belgique.
G.Arribarat, O. Pasternak, O. Rascol, P. Péran.
- > Functional connectivity changes in resting state MRI after donepezil treatment in healthy participants8th European Conference onClinical Neuroimaging, 20-21 Mai 2018, Bruxelles, Belgique.
P Péran, A.-S Salabert, T. Dondaine, J. Sein, J.A. Gutierrez, X. Leclerc, H. Gros-Dagnac, J Llido, J.-P. Ranjeva, R. Lopes, L. Lanteaume, O. Blin, C Thalamas, R Bordet, P Payoux, PharmaCog Consortium
- > Application de la théorie des graphes dans l’exploration des réseaux cérébraux au cours du coma4e Rencontre " Objectif ESOF (EuroScience Open Forum) 2018" - TOULOUSE
Brigitta Malagurski, Patrice Péran, Stein Silva.
- > Explicit motor learning of a synchronization task is improved by auditory (vs visual) stimulations in children with Developmental Coordination Disorder.12th International Conference on Children with Developmental Coordination Disorder. FREMANTLE - AUSTRALIE
Blais, M, Chaix, Y, Biotteau, M, Maziero, S, Jucla. M, Albaret, J.-M, Péran, P, Tallet J.
- > MR imaging predictor of survival in pediatric ependymoma patients after radiotherapyEuropean SocieTy for Radiotherapy and Oncology (ESTRO) - VIENNE
F. Tensaouti, A. Ducassou, L. Chaltiel, A. Sevely, S. Bolle, X. Muracciole, B. Coche-Dequant, C. Alapetite, S. Supiot, A. Huchet,V. Bernier, L. Claude, A.I. Bertozzi-Salamon, P. Péran, P. Payoux, A. Laprie.
- > Cortex cingulaire et anosognosie dans la Maladie d’Alzheimer : étude en imagerie multimodale41ièmes Journées de Printempsde SNLF - GRENOBLE Obtenu Prix de la meilleure communication orale
Laura Guerrier, Johanne Le Men, Anaïs Gane, Mélanie Planton, Anne-Sophie Salabert, Pierre Payoux, Hervé Dumas, Fabrice Bonneville, Patrice Péran, Jérémie Pariente
- > Diffusion tensor imaging of white matter tracts in the normal equidae brainEAVA (European Association of Veterinary Anatomists) - VIENNE
F. Labelle, G. Arribarat, S. Monteil, S. Ken, F. Audigie, H. Gros, JP. Desirat, P. Peran, A. Deviers, G. Mogicato
- > Medial thalamic stroke and its impact on familiarity and recollection.1-BNS-SNLF, British and French Neuropsychological Societies - LONDRES 2-6th International Conference on Memory (ICOM-6) - BUDAPEST
Lola Danet, Jérémie Pariente, Pierre Eustache, Nicolas Raposo, Igor Sibon, Jean-François Albucher, Fabrice Bonneville, Patrice Peran, Emmanuel J.Barbeau
Abstracts rédigés ou co-rédigés
- > 66- Neural Substrates of Psychotic Depression: Findings From the Global ECT-MRI Research Collaboration.
Takamiya A, Dols A, Emsell L, Abbott C, Yrondi A, Soriano Mas C, Jorgensen MB, Nordanskog P, Rhebergen D, van Exel E, Oudega ML, Bouckaert F, Vandenbulcke M, Sienaert P, Péran P, Cano M, Cardoner N, Jorgensen A, Paulson OB, Hamilton P, Kampe R, Bruin W, Bartsch H, Ousdal OT, Kessler U, van Wingen G, Oltedal L, Kishimoto T.
Schizophr Bull. 2021 Oct 8:sbab122. doi: 10.1093/schbul/sbab122. Online ahead of print.PMID: 34624103 - > 55- Prion strains associated with iatrogenic CJD in French and UK human growth hormone recipients.Acta Neuropathol Commun. 2021 Aug 28;9(1):145. doi: 10.1186/s40478-021-01247-x.
Douet JY, Huor A, Cassard H, Lugan S, Aron N, Mesic C, Vilette D, Barrio T, Streichenberger N, Perret-Liaudet A, Delisle MB, Péran P, Deslys JP, Comoy E, Vilotte JL, Goudarzi K, Béringue V, Barria MA, Ritchie DL, Ironside JW, Andréoletti O.
- > 29- Language Network Connectivity Increases in Early Alzheimer’s Disease.J Alzheimers Dis. 2021 May 18. doi: 10.3233/JAD-201584.
Pistono A, Senoussi M, Guerrier L, Rafiq M, Gimeno M, Péran P, Jucla M, Pariente J.
- > 19- Prions from Sporadic Creutzfeldt-Jakob Disease Patients Propagate as Strain Mixtures.mBio. 2020 Jun 16;11(3):e00393-20. doi: 10.1128/mBio.00393-20.
Cassard H, Huor A, Espinosa JC, Douet JY, Lugan S, Aron N, Vilette D, Delisle MB, Marín-Moreno A, Peran P, Beringue V, Torres JM, Ironside JW, Andreoletti O.
- > 1- Iron distribution in the lentiform nucleus: A post-mortem MRI and histology study.Brain Struct Funct. 2021 Jan 2. doi: 10.1007/s00429-020-02175-7.
De Barros A, Arribarat G, Lotterie JA, Dominguez G, Chaynes P, Péran P.
Voir la publication - > 47- Are morphological and structural MRI characteristics related to specific cognitive impairments in neurofibromatosis type 1 (NF1) children?Eur J Paediatr Neurol. 2020 Jul 31:S1090-3798(20)30144-6. doi: 10.1016/j.ejpn.2020.07.003. Online ahead of print.
Baudou E, Nemmi F, Biotteau M, Maziero S, Assaiante C, Cignetti F, Vaugoyeau M, Audic F, Peran P, Chaix Y.
Voir la publication - > 46- Diffusion Tensor Imaging Tractography of White Matter Tracts in the Equine Brain.Front Vet Sci. 2020 Jul 30;7:382. doi: 10.3389/fvets.2020.00382. eCollection 2020.
Boucher S, Arribarat G, Cartiaux B, Lallemand EA, Péran P, Deviers A, Mogicato G.
Voir la publication - > 38- Procedural learning and retention of audio-verbal temporal sequence is altered in children with Developmental Coordination Disorder but cortical thickness matters.Dev Sci. 2020 Jun 23:e13009. doi: 10.1111/desc.13009.
Lê M, Blais M, Jucla M, Chauveau N, Maziero S, Biotteau M, Albaret JM, Péran P, Chaix Y, Tallet J.
Voir la publication - > 28- Functional and Structural Integrity of Frontoparietal Connectivity in Traumatic and Anoxic Coma.Crit Care Med. 2020 May 11. doi: 10.1097/CCM.0000000000004406.
Peran P, Malagurski B, Nemmi F, Sarton B, Vinour H, Ferre F, Bounes F, Rousset D, Mrozeck S, Seguin T, Riu B, Minville V, Geeraerts T, Lotterie JA, Deboissezon X, Albucher JF, Fourcade O, Olivot JM, Naccache L, Silva S.
Voir la publication - > 26- Interhemispheric distribution of amyloid and small vessel disease burden in cerebral amyloid angiopathy-related intracerebral hemorrhage.Eur J Neurol. 2020 May 11. doi: 10.1111/ene.14301.
Planton M, Pariente J, Nemmi F, Albucher JF, Calviere L, Viguier A, Olivot JM, Salabert AS, Payoux P, Peran P, Raposo N.
Voir la publication - > 9- Neuromelanin Locus Coeruleus MRI Contrast in Migraine With Aura.Headache. 2020 Feb 17. doi: 10.1111/head.13771.
Gollion C, Arribarat G, Ruidavets JB, Fabre N, Barège M, Bonneville F, Larrue V, Peran P.
Voir la publication - > 1- Florbetapir Regional Distribution in Cerebral Amyloid Angiopathy and Alzheimer’s Disease: A PET Study.J Alzheimers Dis. 2020 Jan 13. doi: 10.3233/JAD-190625.
Planton M, Saint-Aubert L, Raposo N, Payoux P, Salabert AS, Albucher JF, Olivot JM, Péran P, Pariente J.
Voir la publication - > 53- Multiple System Atrophy: Recent Developments and Future PerspectivesMov Disord. 2019 Nov 6. doi: 10.1002/mds.27894.
Meissner WG, Fernagut PO, Dehay B, Péran P, Traon AP, Foubert-Samier A, Lopez Cuina M, Bezard E, Tison F, Rascol O.
- > 51- Posterior Cortical Atrophy: Does Complaint Match the Impairment? A Neuropsychological and FDG-PET StudyFront Neurol. 2019 Sep 20;10:1010. doi: 10.3389/fneur.2019.01010.
Guerrier L, Cransac C, Pages B, Saint-Aubert L, Payoux P, Péran P, Pariente J
Voir la publication - > 50- Significant Decrease in Hippocampus and Amygdala Mean Diffusivity in Treatment-Resistant Depression Patients Who Respond to Electroconvulsive Therapy.Front Psychiatry. 2019 Sep 19;10:694. doi: 10.3389/fpsyt.2019.00694. Voir la publication
Yrondi A, Nemmi F, Billoux S, Giron A, Sporer M, Taib S, Salles J, Pierre D, Thalamas C, Schmitt L, Péran P, Arbus C.
- > 44- Grey Matter changes in treatment-resistant depression during electroconvulsive therapy.J Affect Disord. 2019 Jul 31;258:42-49. doi: 10.1016/j.jad.2019.07.075.
Yrondi A, Nemmi F, Billoux S, Giron A, Sporer M, Taib S, Salles J, Pierre D, Thalamas C, Rigal E, Danet L, Pariente J, Schmitt L, Arbus C, Péran P.
Voir la publication - > 42- Enlarged perivascular spaces and florbetapir uptake in patients with intracerebral hemorrhage.Eur J Nucl Med Mol Imaging. 2019 Jul 29. doi: 10.1007/s00259-019-04441-1.
Raposo N, Planton M, Payoux P, Péran P, Albucher JF, Calviere L, Viguier A, Rousseau V, Hitzel A, Chollet F, Olivot JM, Bonneville F, Pariente J.
Voir la publication - > 25- A totally data-driven whole-brain multimodal pipeline for the discrimination of Parkinson’s disease, multiple system atrophy and healthy controlNeuroImage Clinical
Nemmi F, Pavy-Le Traon A, Phillips O.R, Galitzky M, Meissner W.G, Rascol O, Péran P
- > 30- Substantia nigra locations of iron-content, free-water and mean diffusivity abnormalities in moderate stage Parkinson’s disease.Parkinsonism Relat Disord. 2019 May 22. pii: S1353-8020(19)30254-8. doi: 10.1016/j.parkreldis.2019.05.033.
Arribarat G, Pasternak O, De Barros A, Galitzky M, Rascol O, Péran P.
- > 24- Discriminating between neurofibromatosis-1 and typically developing children by means of multimodal MRI and multivariate analyses2019;1–14
Nemmi F, Cignetti F, Assaiante C, Maziero S, Audic F, Péran P, Chaix Y
Hum Brain Mapp.
- > 21- Discriminating between neurofibromatosis-1 and typically developing children by means of multimodal MRI and multivariate analyses.Hum Brain Mapp. 2019 May 11. doi: 10.1002/hbm.24612.
Nemmi F, Cignetti F, Assaiante C, Maziero S, Audic F, Péran P, Chaix Y.
- > 24- Impact of spontaneous intracerebral hemorrhage on cognitive functioning: An update.Rev Neurol (Paris). 2017 Jul - Aug;173(7-8):481-489. doi: 10.1016/j.neurol.2017.06.010. Epub 2017 Aug 31. Review.
Planton M, Raposo N, Danet L, Albucher JF, Péran P, Pariente J.
- > 38- Assessment of Translocator Protein Density, as Marker of Neuroinflammation, in Major Depressive Disorder: A Pilot, Multicenter, Comparative, Controlled, Brain PET Study (INFLADEP Study).Front Psychiatry. 2018 Jul 24;9:326. doi: 10.3389/fpsyt.2018.00326. eCollection 2018.
Yrondi A, Aouizerate B, El-Hage W, Moliere F, Thalamas C, Delcourt N, Sporer M, Taib S, Schmitt L, Arlicot N, Meligne D, Sommet A, Salabert AS, Guillaume S, Courtet P, Galtier F, Mariano-Goulart D, Champfleur NM, Bars EL, Desmidt T, Lemaire M, Camus V, Santiago-Ribeiro MJ, Cottier JP, Fernandez P, Meyer M, Dousset V, Doumy O, Delhaye D, Capuron L, Leboyer M, Haffen E, Péran P, Payoux P, Arbus C.
- > 37- Involvement of the Cingulate Cortex in Anosognosia: A Multimodal Neuroimaging Study in Alzheimer’s Disease Patients.J Alzheimers Dis. 2018 Jul 20. doi: 10.3233/JAD-180324.
Guerrier L, Men JL, Gane A, Planton M, Salabert AS, Payoux P, Dumas H, Bonneville F, Péran P, Pariente J.
- > 51- Imaging biomarkers of outcome after radiotherapy for pediatric ependymoma.Radiother Oncol. 2018 Apr;127(1):103-107. doi: 10.1016/j.radonc.2018.02.008.
Tensaouti F, Ducassou A, Chaltiel L, Sevely A, Bolle S, Padovani L, Jouin A, Alapetite C, Supiot S, Huchet A, Bernier V, Claude L, Kerr C, Le Prisé E, Bertozzi-Salamon AI, Liceaga S, Lotterie JA, Péran P, Laprie A; French Society for Childhood Cancer (SFCE).
- > 8- Imaging biomarkers of outcome after radiotherapy for pediatric ependymoma.French Society for Childhood Cancer (SFCE). Radiother Oncol. 2018 Feb 27. pii: S0167-8140(18)30064-1. doi: 10.1016/j.radonc.2018.02.008.
Tensaouti F, Ducassou A, Chaltiel L, Sevely A, Bolle S, Padovani L, Jouin A, Alapetite C, Supiot S, Huchet A, Bernier V, Claude L, Kerr C, Le Prisé E, Bertozzi-Salamon AI, Liceaga S, Lotterie JA, Péran P, Laprie A;
- > 5- MRI supervised and unsupervised classification of Parkinson’s disease and multiple system atrophy.Mov Disord. 2018 Feb 23. doi: 10.1002/mds.27307.
Péran P, Barbagallo G, Nemmi F, Sierra M, Galitzky M, Traon AP, Payoux P, Meissner WG, Rascol O.
- > 42- Medial thalamic stroke and its impact on familiarity and recollection.Elife. 2017 Aug 24;6. pii: e28141. doi: 10.7554/eLife.28141.
Danet L, Pariente J, Eustache P, Raposo N, Sibon I, Albucher JF, Bonneville F, Péran P, Barbeau EJ.
- > 43- Impact of spontaneous intracerebral hemorrhage on cognitive functioning: An update.2017 Aug 21. pii: S0035-3787(17)30543-X. doi: 10.1016/j.neurol.2017.06.010.
Planton M, Raposo N, Danet L, Albucher JF, Péran P, Pariente J. Rev Neurol (Paris).
- > 38- Florbetapir imaging in cerebral amyloid angiopathy-related hemorrhages.Neurology. 2017 Jul 19. pii: 10.1212/WNL.0000000000004228. doi: 10.1212/WNL.0000000000004228.
Raposo N, Planton M, Péran P, Payoux P, Bonneville F, Lyoubi A, Albucher JF, Acket B, Salabert AS, Olivot JM, Hitzel A, Chollet F, Pariente J.
- > 27- High prevalence of cognitive impairment after intracerebral hemorrhage.PLoS One. 2017 Jun 1;12(6):e0178886. doi: 10.1371/journal.pone.0178886. eCollection 2017.
Planton M, Saint-Aubert L, Raposo N, Branchu L, Lyoubi A, Bonneville F, Albucher JF, Olivot JM, Péran P, Pariente J.
- > 16- Brain Gray Matter MRI Morphometry for Neuroprognostication After Cardiac Arrest.Crit Care Med. 2017 Mar 7. doi: 10.1097/CCM.0000000000002379.
Silva S, Peran P, Kerhuel L, Malagurski B, Chauveau N, Bataille B, Lotterie JA, Celsis P, Aubry F, Citerio G, Jean B, Chabanne R, Perlbarg V, Velly L, Galanaud D, Vanhaudenhuyse A, Fourcade O, Laureys S, Puybasset L.
- > 66- Neural Signature of DCD: A Critical Review of MRI Neuroimaging Studies.Front Neurol. 2016 Dec 16;7:227. doi: 10.3389/fneur.2016.00227
Biotteau M, Chaix Y, Blais M, Tallet J, Péran P, Albaret JM.
- > 41- Identification of a candidate biomarker from perfusion MRI to anticipate glioblastoma progression after chemoradiation.Eur Radiol. 2016 Nov;26(11):4194-4203.
Khalifa J, Tensaouti F, Chaltiel L, Lotterie JA, Catalaa I, Sunyach MP, Ibarrola D, Noël G, Truc G, Walker P, Magné N, Charissoux M, Ken S, Peran P, Berry I, Moyal EC, Laprie A.
- > 53- Prognostic and predictive values of diffusion and perfusion MRI in paediatric intracranial ependymomas in a large national study.Br J Radiol. 2016 Oct;89(1066):20160537. doi: 10.1259/bjr.20160537.
Tensaouti F, Ducassou A, Chaltiel L, Sevely A, Bolle S, Muracciole X, Coche-Dequant B, Alapetite C, Supiot S, Huchet A, Bernier V, Claude L, Bertozzi-Salamon AI, Liceaga S, Lotterie JA, Péran P, Payoux P, Laprie A; radiotherapy committee of the French Society for Childhood Cancer (SFCE)..
- > 59- Do perfusion and diffusion MRI predict glioblastoma relapse sites following chemoradiation?J Neurooncol. 2016 Oct;130(1):181-192.
Khalifa J, Tensaouti F, Lotterie JA, Catalaa I, Chaltiel L, Benouaich-Amiel A, Gomez-Roca C, Noël G, Truc G, Péran P, Berry I, Sunyach MP, Charissoux M, Johnson C, Cohen-Jonathan Moyal E, Laprie A.
- > 39- Multimodal Magnetic Resonance Imaging in Alzheimer’s Disease Patients at Prodromal Stage.J Alzheimers Dis. 2016;50(4):1035-50. doi: 10.3233/JAD-150353.
Eustache P, Nemmi F, Saint-Aubert L, Pariente J, Péran P.
- > 34- Multimodal MRI assessment of nigro-striatal pathway in multiple system atrophy and Parkinson disease.Mov Disord. 2016 Mar;31(3):325-34. doi: 10.1002/mds.26471.
Barbagallo G, Sierra-Peña M, Nemmi F, Traon AP, Meissner WG, Rascol O, Péran P.
- > Thalamic amnesia after infarct: The role of the mammillothalamic tract and mediodorsal nucleus.Neurology. 2015 Dec 15;85(24):2107-15. doi: 10.1212/WNL.0000000000002226.
Danet L, Barbeau EJ, Eustache P, Planton M, Raposo N, Sibon I, Albucher JF, Bonneville F, Peran P, Pariente J.
- > Disruption of posteromedial large-scale neural communication predicts recovery from coma.Neurology. 2015 Dec 8;85(23):2036-44. doi: 10.1212/WNL.0000000000002196.
Silva S, de Pasquale F, Vuillaume C, Riu B, Loubinoux I, Geeraerts T, Seguin T, Bounes V, Fourcade O, Demonet JF, Péran P.
- > Voxel-based evidence of perfusion normalization in glioblastoma patients included in a phase I-II trial of radiotherapy/tipifarnib combination.J Neurooncol. 2015 Sep;124(3):465-73. doi: 10.1007/s11060-015-1860-8.
Ken S, Deviers A, Filleron T, Catalaa I, Lotterie JA, Khalifa J, Lubrano V, Berry I, Péran P, Celsis P, Moyal EC, Laprie A.
- > Parkinson’s disease and local atrophy in subcortical nuclei: insight from shape analysis.Neurobiol Aging. 2015 Jan;36(1):424-33. doi: 10.1016/j.neurobiolaging.2014.07.010.
Nemmi F, Sabatini U, Rascol O, Péran P.
- > Insight on AV-45 binding in white and grey matter from histogram analysis: a study on early Alzheimer’s disease patients and healthy subjects.Eur J Nucl Med Mol Imaging. 2014 Jul;41(7):1408-18. doi: 10.1007/s00259-014-2728-4.
Nemmi F, Saint-Aubert L, Adel D, Salabert AS, Pariente J, Barbeau EJ, Payoux P, Péran P.
- > Comparison between PET template-based method and MRI-based method for cortical quantification of florbetapir (AV-45) uptake in vivo.Eur J Nucl Med Mol Imaging. 2014 May;41(5):836-43. doi: 10.1007/s00259-013-2656-8.
Saint-Aubert L, Nemmi F, Péran P, Barbeau EJ, Payoux P, Chollet F, Pariente J.
Publications rédigées ou co-rédigées
Encadrements de thèse en cours:
Functional connectivity
The approach: cross-correlation matrix computed from resting session. de Pasquale F, Sabatini U, Della Penna S, Sestieri C, Caravasso CF, Formisano R, Péran P. Neuroimage, 2013
SMA network
Iron brain mapping
Indirect validation: strong correlation between theorical [Fe] and R2* measure
Péran et al., HBM, 2009
Development of high resolution R2* maps using relaxometry
Péran et al., HBM, 2009
The multimodal MRI approach
Methods: Measure of several quantitative parameters
Application in Parkinson’s disease (PD)
MRI PD nigrostriatal signature
-> Able to discriminate PD patients and controls !
Péran et al., Brain, 2010
Neuroimaging & Neuropsychology: Mental representation of action
Healthy subjects
Areas jointly activated by semantics of action and mental representations of action
Péran et al., Brain Res, 2010
Movement disorders diseases
Specific verb impairment in PD patients
Péran et al., Mvt Disord, 2003
Global impairment in HD patients
Péran et al., Mvt Disord, 2004
fMRI in PD patients
Activation maps of positive correlations between each condition and the motor deficit
Péran et al., Cortex, 2009
Péran et al., Brain Lang, 2012